What Happens to the Brain During an Affair?

What Happens to the Brain During an Affair?

Affairs in film and television series are often portrayed as exciting adventures, fun and mischievous; a way of breaking free from oppression… a conduit to a joyful existence. To the person contemplating an affair, it can seem like a solution to depression, boredom or worse in a marriage; desperately needed relief from intense loneliness, and/or a bolster to one’s self esteem.

The reality of the experience of an affair is almost always very different. The explosion of brain research in the last decade has shed light

on some of what actually happens physiologically. There are major changes in how the brain functions when one is infatuated, in love, and also when one is keeping a secret.

Falling in Love

Two major brain changes take place during infatuation.

The first is a flood of the neurotransmitter dopamine. One of the functions of dopamine is to heighten the sensation of pleasure. Dopamine also increases energy, hence that first animated, exciting conversation. Another interesting part of the dopamine response is that the next time  one sees that person, before  even talking to them, dopamine again floods the system. This person has now become associated with intense pleasure.

The second change is that the level of another neurotransmitter, serotonin, decreases. There are three effects associated with decreased serotonin levels that are important to understand here. The first is the subjective feeling of emptiness. The second is obsessive anxiety. The brain is literally runs the person away from the emptiness towards the person who has become the object of obsession. The third effect is sleep disturbances, which I’ll discuss further below.


Let’s say these brain changes are resolved by going ahead with the affair. Now the hormone oxytocin floods the system. Oxytocin is associated with love. It is released during hugging, kissing, and cuddling and it makes you want to do these things more. It makes you more emotionally open in general, which is why many people during the earlier stages of affairs experience an enhanced sense of well-being and believe that the affair is good for them. The more time spent with the affair partner, the more oxytocin is released, which again increases the desire for emotional intimacy with the person who is the object of the obsession.

Keeping the Secret

A part of the brain called the cingulate cortex is essential to our emotional responses. It is wired to tell the truth. The cingulate cortex signals other regions of the brain to share information so it can move on to more important functions, like planning, problem solving, learning, reflecting, etc. But when a secret is locked inside, the cingulate cortex is not allowed to perform its natural functions. Instead, the cortex becomes stressed and releases stress hormones, such as cortisol.

This is where the negative effects start to cascade. Increased cortisol levels negatively affects attention, memory, blood pressure, appetite, digestion, metabolism, and sleep to name a few. Not getting enough sleep, can lead to mood swings, depression, irritability, difficulty controlling one’s temper, and, when faced with a perceived threat, the “fight or flight” response. Physiologically, speaking, this is why people in affairs get angry, enraged, or withdrawn when questioned about it by their spouses. Increases in cortisol are also associated with a lowered immune response, so illness during this time is not uncommon.

Frequently, somewhere inside of this cascade a desperation for emotional relief can arise. This desperation can lead some to turn to alcohol, or other addictive substances to try to numb the stress and anxiety. But substance abuse brings a host of it’s own problems, compromising one’s physical, mental and emotional functioning further, and exacerbating conflicts with others.

This is a lot to think about, but one conclusion stands out. As one gets more deeply involved in an affair, there is less and less emotional and physical capacity to handle it. Juggling two primary relationships, as well as keeping the secret in general, can be exhausting. The nervous system is compromised and stressed, sometimes to what can feel like a breaking point.

The Antidote

What I have described above has many similarities to the physiological effects of addiction . The antidote to addiction is, of course, stopping and facing withdrawal. Withdrawal from a love relationship has been shown to be physiologically similar in intensity and quality to withdrawal from heroin.  No wonder so many people in unhappy relationships are afraid to let go.

But an affair is only an affair as long as it is a secret. Coming clean about an affair might mean disclosing it to one’s spouse.  Although this can be extremely painful, there can also be a kind of relief, even if it means facing extreme marital discord for a while, including the threat of divorce.  Another option is disclosing to a therapist where the costs, benefits and meanings of what has happened can be explored.

Once the affair is disclosed, the next step can become self-evident. This might mean ending the affair. It might mean living on one’s own for a while. It might mean ending your marriage. (Some affairs are unconscious attempts to do this.) It might mean talking with a therapist individually about what has happened to you and clarifying feelings and priorities. It might be an opportunity to explore issues in your marriage that you thought you could never address with your spouse, with a marriage counselor.

I have seen hundreds of individuals and couples struggling with these issues. If you are thinking that individual psychotherapy or marriage counseling may be beneficial and you live in the San Francisco Bay Area, please feel free to contact me. If you live outside of the area, please visit my “Links” page for a geographical listing of therapists who are especially effective with affairs.

8 thoughts on “What Happens to the Brain During an Affair?

  1. I finally was able to get my wife to tell me and everyone about her feelings and how she is trying to move on. She is sorry that she did what she did but the guy has done this with another woman. I know that they had a connection but I think that its because my wife has the most amazing caring heart. She was having to move from having all of our children needing her to all of them in school and her questioning everything that she was. I always worked and provided for them but it was not enough. I knew she had been having an affair for almost a year. I was trying to get it out in the open but was unable to because of what seemed to be a soap opera that has so many twists and turns.

    I am now trying to put everything together. She has said that there are two choices; divorce or trying. I have had many break downs because she has continued to defend the guy. She is mad that I told him to stop talking to her and wanted to keep his friendship with him but how can you allow that when you know that it was him that was chasing after her? He honestly is the guy that everyone associates with being dishonest, self absorbed and manipulative. He went back to his wife but continued to dangle her on the hook and she continued to want that. The issue I am having is that I know that she has lied about what she really wants to my face. I want to trust her because I have such a connection with her but how can you trust someone that wanted someone that bad and did all she did to cover it up. She has said that we will always be friends and that to me seems like the end is near. Facebook is the source of all this because of how easy it is to approach someone on there.

    What can I do but trust that I am going to be the one that she wants. I know that the big issue that she now has is that she is used to the comfortable lifestyle I have given her as well as the kids and their involvement in different activities. She also has told me time and time again that she does not want to tell me the truth because she does not want to hurt me.

    What can someone that is trying to getting past this do?

  2. WOW, Awesome. Excellent article.

    I am in year four of an affair with a married woman. I am not the first she has had an affair with. Her spouse emotionally abused her for their entire marriage, and she has had several breakdowns (anxiety depression).

    She wants to end her marriage, but he has severe anger issues, and she fears for her safety. He has OCD and anger issues. But, he has never physically hit her.

    We both have adult children
    We are committed to live the rest of our lives together.

    But need help in how to move forward under these challenging conditions.

  3. So so glad I read this. I would do anything to get out of the affair but I can’t. It’s having an awful impact on my health and I just wish everything would end for me.

  4. Wow best article I’ve read by far on this topic. I’m experiencing everything that’s written here, and still trapped.

  5. Don’t forget to remember your spouse. The longer your affair continues the harder it is to repair and rebuild. You might think 3 or 4 years, what’s the difference? But once it’s all out she or he will look back and everything you did and said during that time will mean nothing and will be a huge slap in the face! To all of the spouses who are doing the cheating please put yourself in their position and if you can truly say you would be okay with everything you are doing, then go ahead. But I can’t imagine any human being okay with being deceived on a daily basis for months or even years. Why not make a choice and pick one? It can not stay this way forever and if you wait till your spouse finds out you might loose everything!! Have some compassion for the person you vowed to love and cherish and make a choice!

  6. Great article very interesting explains a lot and makes sense based on what I am feeling in year 3 of my affair.

  7. This is all so true. I wish I had never got involved in the deception of an affair. It felt so good (at first) but now the highs don’t outweigh the lows. I can’t break free – it hurts too much.

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